Sentence examples for mutation carriers when from inspiring English sources

The age of the mutation carriers when they had PSA tests was on average 66 years (range 49 89).

There was no evidence of an association of rs6917 with breast or ovarian cancer risk for mutation carriers when the risks were evaluated separately (Table 2).

They found that the mutation carriers when compared with controls had a significantly higher incidence of extramedullary disease and a shorter overall survival.

Based on the current knowledge, it is reasonable to recommend prophylactic oophorectomy for BRCA1 or BRCA2 mutation carriers when childbearing is completed in order to reduce the risk of developing breast and ovarian cancer.

There was no evidence of association between the PHB 1630 C>T and MTHFR 677 C>T polymorphisms with either disease for BRCA1 or BRCA2 mutation carriers when breast and ovarian cancer associations were evaluated separately.

In BRCA2, all four common variants were found to occur less frequently in the deleterious mutation carriers when compared to non-carriers, but the evidence for difference in the distribution between the two groups was weak (p = 0.16).

The exception was mothers of a mutation carrier when it was clear that the mutation was paternally inherited.

In developing the LAMBDA model we have considered those personal and family cancer history features that have been reported to influence the probability of being a mutation carrier when considered on their own.

We did not find any significant differences between tumours originating from different mutation carriers or when comparing tumours from the carriers of mutations from the OCCR Ovarian Cancer Clusterregionon) (n = 7) and the end of the gene.

Four reports found that psychotic features (particularly delusions) were frequent among mutation carriers, particularly when present early during the disease course, suggesting that this symptom category may be a marker for the mutation.

A protective effect of incomplete pregnancies among BRCA2 mutation carriers remained when we assessed the relationship between the total number of spontaneous and therapeutic abortions and breast cancer risk.