Sentence examples for mutation carriers have from inspiring English sources

Mutations in the presenilin genes cause early-onset familial Alzheimer's disease, but mutation carriers have substantial phenotypic heterogeneity.

Mutation carriers have a risk of developing CRC of approximately 50 82 % throughout their lifetime, with occasional relapses after treatment [5, 9, 10].

So far, 57 HNF-1α mutation carriers have been identified.

Heterozygous mutation carriers have a later age of diabetes onset.

The pathological features of breast tumors arising in BRCA1 mutation carriers have been extensively described.

Atypical and unusual histologic features of breast cancers in BRCA1 mutation carriers have been reported.

Tumors arising in mutation carriers have generally lost the wild-type BRCA1 allele [ 2].

A total of 984 mutation carriers have been detected (547 affected with breast cancer, 437 unaffected).

Tumour cells from germline mutation carriers have frequently lost the wild-type allele.

Recently the effects of educational-support groups for BRCA mutation carriers have been studied [ 46].

Forty-four per cent of the HNF1B mutation carriers have hypomagnesaemia, hypermagnesuria and hypocalciuria [ 70].