Sentence examples for mutation carriers furthermore from inspiring English sources

Germline SDH gene mutation analyses, performed in 34 cases, identified 13 mutation carriers, furthermore CNV analysis identified a large germline deletion/rearrangement of SDHB in one additional case (8PTJ, confirmed by NFMP-HPLC).

While the hormone receptor or HER2 status has seldom been specified in previous papers, a single study [ 19] found predominant hormone receptor negativity among MMR-deficient breast cancers from MMR gene mutation carriers; furthermore, there was no difference in the age at onset between MMR-deficient and MMR-proficient breast cancers.

Furthermore, BRCA1/2 mutation carriers also have a higher rate of pregnancy-associated breast cancer before the age of 50[ 21] 21].

Furthermore, Parkin mutation carriers showed a slightly reduced ability to recognize facial emotions that was least severe in individuals who showed the strongest increase of ventrolateral premotor activity.

Furthermore, KCNJ5 mutation carriers are generally younger than nonmutated APA patients, which suggests earlier disease onset and/or more severe disease and thus earlier diagnosis.

Furthermore, GBA mutation carriers exhibit parkinsonian phenotypes and present a diffuse pattern of LB distribution in the cerebral cortex (do Rosário Almeida 2012).

Furthermore, identified asymptomatic mutation carriers might also have the opportunity to join treatment trials for genetic at-risk groups, such as the Alzheimer's Prevention Initiative and Dominantly Inherited Alzheimer Network initiatives [ 118].

Furthermore, since BRCA mutation carriers develop fallopian tube carcinoma and peritoneal papillary serous carcinoma, PBSO and sectioning both tubes and ovaries is therefore recommended in order to ensure occult carcinomas are not missed[ 31].

Furthermore, observational studies of BRCA mutation carriers suggest that 50% of breast cancers in this population present between screening mammograms [ 4, 7].

Furthermore, after exclusion of 13 mutation carriers who had been recruited because of family history, the interaction remained statistically significant (P = 0.005 and P = 0.021 for the number of births and for the duration of breast feeding, respectively).

Furthermore, in this French study BRCA mutation carriers have to be older than 35 to be included.