Sentence examples for mutation carriers also from inspiring English sources

Consistent with this finding, two breast cancer cell lines from BRCA1 mutation carriers also clustered in basal-A (and basal-A lines exhibited enrichment of a BRCA1 signature), where it has been established that BRCA1-associated tumors share many features with sporadic basal-like tumors [80].

AKT2 mutation carriers also have reduced adipose tissue content.

Within the parietal lobule, mutation carriers also showed differential activations compared with controls.

The PSEN1 mutation carriers also underwent neurological examination and detailed neuropsychological assessment.

Importantly, we show that the development of TNBCs in BRCA1 mutation carriers also depends on RB/p16 dysfunction.

Women who are BRCA1/2 mutation carriers also have a 26 40% risk of contralateral breast cancer in 10 years [ 5, 6].

Whether incorporation of OPTN in ALS aggregates in non-mutation carriers also results in loss of function of the protein or merely reflects its role as an autophagic receptor warrants further investigation.

An understanding of these mechanisms is relevant not only to families with BRCA1 and BRCA2 mutation carriers but also in sporadic breast cancer, in which the same or related genetic pathways may also be aberrant.

The number of mutation carriers was also relatively small (182 BRCA1 mutation carriers and 64 BRCA2 mutation carriers).

The issue of mutation carriers can also be clarified in the criteria.

Moreover, BRCA1 and BRCA2 mutation carriers are also at increased risk of pancreatic, prostate, and endometrial cancer.