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At least one mutation carrier was found in 112 prostate cancer families (4.6 %), all of European descent.
If volunteers from the same family included a mutation carrier and a non-carrier, the mutation carrier was used as the proband.
The controls had to have been alive when their matched mutation carrier was diagnosed.
Case 1: This Caucasian female (ΔGAG mutation carrier) was 89 years old at death.
No mutation carrier was found among 118 unselected Jewish individuals of Iranian origin.
In the present study, no mutation carrier was discovered among the 190 patients with borderline tumours.
Similar(41)
On the other hand, a localized ovarian tumour in a BRCA2 mutation carrier is presented in Fig. 3.
The lifetime risk of developing PAH in a BMPR2 mutation carrier is less than 20%[ 4].
94 The optimal timing of prophylactic surgery for an asymptomatic BRCA mutation carrier is highly personal.
The age-related decline in telomere lengths of the TERT mutation carriers was similar to that of the normal controls.
However, the number of BRCA2 mutation carriers was relatively small.
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