Sentence examples for mutation carriage from inspiring English sources

Moreover, the mother gene mutation carriage was proven.

In her family, however, the level of C-peptide did not differ significantly upon the dependency of mutation carriage.

Guideline organizations, including NCCN and ASCO, have advised targeting BRCA1 and BRCA2 testing to probands whose probability of mutation carriage is approximately 10% or greater.

This observation was confirmed by the Kaplan-Meier method as the K8E1 mutation carriage was not associated with the development of HCC (HR=0.8 [0.1–3.3], log-rank=0.7) or death (HR=0.4 [0.1–1.6], log-rank=0.2) when considering the occurrence of these events over time.

A recent study in the Netherlands reported a high proportion (61%) of lpxL1 mutations among 71cc233 carriage isolates (predominantly MenY) compared with 0.3% among 751 non-cc23 carriage isolates and 8.6% among 464 non-cc23 invasive disease isolates (31 ).

However, we found no evidence this was linked to carriage of mutations in the dhfr and dhps genes, which was high in all treatment groups.

High-risk women were defined as a 5-year Gail risk for developing invasive breast cancer of at least 1.7%, a prior history of invasive breast cancer or carcinoma in situ, or known carriage of a mutation in either the BRCA1 or BRCA2 gene (although only three women were BRCA1 or BRCA2 mutation carriers, accounting for < 1% of the study population).

Carriage of CCR5 -2459G mutation has been associated with reduced density of CCR5 on CD14+ monocytes and lower levels of R5 HIV propagation when compared to CCR5 -2459A [40], [40].

To evaluate the association between carriage of BRCA1/2 mutations and ovarian performance, as demonstrated by in vitro fertilization (IVF) outcomes.

Additionally, mice deficient in mast cells due to their carriage of the Kitwsh/wsh mutation showed more severe weight loss and higher-grade pneumonia compared to WT mice infected with M. pulmonis.

The lack of association can be explained by recent publications showing that heterozygous carriage of the TLR4 Asp299Gly mutation does not affect LPS responsiveness and that only the rare homozygous carriers are less responsive to LPS[ 18].