Sentence examples for mutation can lead from inspiring English sources

For example, in hereditary nonpolyposis colon cancer (HNPCC), MLH1 inactivation via mutation can lead to microsatellite instability (MSI) and tumorigenesis, whereas in sporadic colon cancers, MLH1 is frequently silenced by methylation (Kane et al., 1997; Veigl et al., 1998).

This is because only one specific mutation can lead to cross-resistance, while many mutations can confer resistance against only one drug.

An important finding is that spread of an incompletely repressing mutation can lead directly to the elimination of the Wolbachia-infection, or to a lower equilibrium frequency, depending primarily on the penetrance e.

PS-1 mutation can lead to the familiar Alzheimer's disease.

How the same mutation can lead to different phenotypes in different families remains to be elucidated.

Recent genetic work shows that a rare genetic mutation can lead to either epilepsy or schizophrenia.

Second, some nonsense or frameshift mutations can lead to the complete absence of a protein.

But in the last 20 years, with the discovery that both chemical toxins and genetic mutations can lead to similar disorders, scientists are beginning to unravel the process that leads to the death of brain cells and, ultimately, rigidity, tremors and other symptoms of Parkinson's.

Oxidative damage to DNA can cause mutations, and mutations can lead to cancer.

These mice reflect the situations in humans in which point mutations can lead to protein malfunction and disease development.

A single misplaced letter, caused by random mutations, can lead the cells to produce a defective form of the glue.