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Thus, strains with a single mutation can appear susceptible to fluoroquinolones but highly resistant to quinolones [53].
Thus, strains with a single mutation can appear susceptible to fluoroquinolones but highly resistant to quinolones [ 53].
It has been demonstrated that the T790M mutation can appear as a secondary mutation in tumor cells already harboring a sensitizing EGFR mutation.
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Additionally, mutations can appear in the form of mutation series (see the above example).
One of the reasons for the suboptimal performance in predicting unseen proteins could be that we optimised the four methods employing the unseen-mutation cross-validation (different mutations of the same protein can appear in different folds).
As μ increases, sequences at a distance of two and more mutations from the parental molecule can appear in a single replication event.
New genes in the host and parasite populations can appear through either mutation or the influx of genes from other populations.
By contrast, the multiple mutations model [ 17- 19] assumes that beneficial mutations have a single characteristic selective value and can appear in any genetic background, including those containing beneficial mutations generated previously and still not fixed.
When purifying selection is weak and mutation is biased, constrained regions can even evolve faster than neutral sequences and thus can appear to be under positive selection.
Cracks can appear.
The results can appear devious.
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