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The same mutation can also cause ovarian cancer.
We show how the magnitude, type, and timing of mutation can also affect fitness, invasion and diversification.
Mutation can also change the population of nonnative contacts [30].
The observed mutation can also be verified by conventional sequencing.
We and others have recently demonstrated that the V600E mutation can also preclude responsiveness to panitumumab or cetuximab in mCRC patients and cellular models of CRC [20].
We also mutated F1081 in the FABD helix-3 to glutamic acid in BCR63-ABL because this single substitution mutation can also inhibit F-actin binding [38].
Similar(31)
Mutations can also allow cancer cells to resist targeted cancer therapy.
Keratin mutations can also cause deformations in the hair, nails, and corneas.
American geneticist Hermann Joseph Müller showed that new alleles (called mutations) could be produced at high frequencies by treating cells with X-rays, the first demonstration of an environmental mutagenic agent (mutations can also arise spontaneously).
The nature of these mutations can also be characterized by restriction fragment length polymorphisms (RFLP).
These results underscore that distant mutations can also play role in optimizing efficiency via their contribution to the reorganization energy.
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