Sentence examples for mutation by setting from inspiring English sources

For panel C, we start with an initial state with σGF = σRTKi = ON and introduce a RAS activating mutation by setting fRAS = ON for time ≥ 20.

For our analysis of all combined reads (ABC), we generated a mutation list by setting the following cutoffs: an allele frequency between 0.2 and 0.8, a minimum read depth of 4, average hits ≤1, and a MAQ consensus quality score of 40.

The S409A mutation was simulated by setting the MITF phosphorylation rate constant to zero.

The MITF S409A mutation was simulated by setting the MITF S409 phosphorylation rate constant to zero.

The mutation is simulated by setting all four MITF-PIAS3 association rate constants to zero.

After validating the single copy genes, our mutation detection pipeline was improved by setting the mutations at the ratio of non-reference nucleotide number counts of rows to columns at each position (variant multipliers), which ranged from 8to1414 at the minimum non-reference nucleotide percentage of 0.05% and Phred quality scores ranging from 16 to 23.

We avoid the restrictions by setting mutation rates independently for hosts and parasites and allowing for stochastic adoption of mutations.

A putative resistance mechanism can be evaluated in the model by changing the logical rule of a node suspected to be responsible for the observed resistance (e.g., an activating RAS mutation can be introduced by setting fRAS = ON), and testing its effect on the rest of the network.

Finally, we would like to mention that such side effects – narrowing the "width" of quasi-species distribution by setting mutation rate to zero affects the population dynamics at ecological time scale – can happen in wider classes of ecological systems (e.g., see van der Laan and Hogeweg (1994) Proc R Soc Lond B 259 35).

In addition, the conditional model can compensate for a tree that fits the target data poorly by setting the mutation rate to infinity and thereby assuming the data to be IID.

That the observed radiation is actually a polymorphism can be shown by setting the mutation rate to zero.