Sentence examples for mutation by combining from inspiring English sources

We filtered the most pathological mutation by combining the scores of then above servers.

The findings here provide further information specifically with respect to older BRCA1 and BRCA2 patients and warrant further studies for evaluating the probability of mutation by combining information on family history and tumour characteristics in the various age groups.

The individualised vaccines target the rich T-cell-druggable mutanome, exploiting the mutations by combining NGS discovery with systematic immunogenicity analysis of mutations, followed by on-demand RNA drug synthesis.

The additive effect of mutations was analyzed by combining mutations through site-directed mutagenesis.

We designed EGFR mutation detection assays by combining allele-specific PCR amplification with the detection of SYBR Green I fluorescence, and optimized PCR conditions to specifically amplify mutant alleles.

Step 1: A mutation matrix is obtained by combining somatic mutations and CNVs, and an expression matrix is generated from gene expression profiles.

For instance, mutations in overexpressed genes can be found by combining mutations from exome resequencing with gene expression computed from transcriptome sequencing.

Attenuated vaccine viruses are thought to be safe because multiple mutations are required to make them pathogenic, however, if the strains contained in a multivalent vaccine are attenuated via different suites of mutations, then recombination could produce pathogenic viruses by combining mutation-free genome regions from multiple strains.

We provide a general framework for association testing with rare variants by combining mutation information across multiple variant sites within a gene and relating the enriched genetic information to disease phenotypes through appropriate regression models.

Evolutionary networks counteract that shortcoming by combining mutation and recombination models into one.

By combining mutation disease associations and their functional effects new inferences can be made about molecular functions altered in disease.