Sentence examples for mutation burden in from inspiring English sources

Gender Disparity and Mutation Burden in Melanoma.

At present, nothing is known about somatic mutation burden in human SCs or SkM.

Our analyses are the first to demonstrate a gender difference in mutation burden in cutaneous melanoma.

Martin, S. D. et al. Low Mutation Burden in Ovarian Cancer May Limit the Utility of Neoantigen-Targeted Vaccines.

Moon, S. H. et al. Correlations between metabolic texture features, genetic heterogeneity, and mutation burden in patients with lung cancer.

First, we found a negative correlation between the number of cells able to proliferate and differentiate and the average mutation burden in our biopsies.

It is currently not possible to determine whether the marked inter-tumour variability in mutation burden observed in our patient cohort results from tumour sampling bias, or represents true differences in clonality, wherein some tumour cells contain mutations and other do not.

Our results suggest that there is greater richness of T cell clones in primary lung cancers than their paired metastases despite the higher mutation burden observed in metastatic lesions.

It is thus likely that the detrimental mutation burden was larger in the stressful environment than in the permissive environment.

The mutation burden per gene in the cohort of patients with PA was compared to that in a control cohort comprising 724 unaffected parents of patients with congenital heart disease sequenced to similar depth of coverage on the same exome platform (Zaidi et al., 2013) using Fisher's exact test.

There was no significant correlation of mutation burden with age in healthy controls (r = 0.62, P = 0.14).