Sentence examples for mutation bound less from inspiring English sources

For cSti1, the M705V mutation bound less tightly (Kd=0.20±0.03 μM) than the wild-type protein (Kd=0.04±0.01 μM; Figures 6c and 6d).

Phosphorylated mimic S423D bound less STX17 (Fig. 5b).

In contrast, Endo-K4A4 bound less well and Endo-DAH bound membranes slightly better than the WT protein.

As expected, the M705V mutation bound CHIP with more or less equal affinity (Kd=6.7±0.62 μM) relative to wild-type Hsp90 (Kd=4.2±0.63 μM; Figures 6a and 6b).

The material also binds less strongly to water molecules.

(D ) Mutant Pdcd4 binds less efficiently to eIF4A than wildtype.

Alternatively, they may be bound by less potent NFI activators.

Accordingly, β T238A αβ-tubulin should bind less tightly to a TOG domain if the β T238A mutation appreciably changes the conformation of αβ-tubulin, for example by straightening it.

Moreover, a drug with multiple so-called 'off-target' effects binds less precisely to its target kinases and is for that reason less sensitive for dislodging due to a mutation of the target kinase [ 87].

TFs are less abundant, bind less stably to DNA and are more difficult to ChIP.

They were bound to become less and less effective.