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Also, under the pressure of inhibitor, the tumor can develop secondary mutation because of its genetic instability.
My doctor strongly recommended that I get tested for the BCRA gene mutation because of my family and personal history.
This is in contrast to livestock populations, where association testing can detect significant associations a long way from the causative mutation because of long-range LD.
In humans, it is difficult to differentiate the specific effects of each mutation because of the relatively low incidence of the disease and high level of phenotypic variation.
A genomic DNA sample was analysed for DTDST mutation because of clinical and radiographic signs similar to reported cases of rMED [ 9, 10].
When assaying for insertion/deletion events, some reporter loci influence the type of mutation because of reading frame constraints, the requirement for active transcription, the proximity and orientation with respect to origins of replication, and/or unusual chromatin structure.
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The tandem array of duplicates maintained by this selection are subject to a high rate of beneficial mutations because of the increased number of mutational targets; again in this case, NAHR has rapidly produced a large set of Abp mutational targets.
The reason for dividing amino acids into seven groups is that amino acids within the same class likely involve synonymous mutations because of their similar characteristics.
"We might be especially prone to such mutations because of the high number of cell divisions that it takes to build a large human brain," Evrony, the 15th winner of the prize suggests.
In the all-or-nothing scenario, a strong increase in proportion occurs for viruses that have acquired all mutations because of its substantial fitness advantage over the rest of the population.
Amino acids within the same groups likely involve synonymous mutations because of their similar characteristics [ 29].
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