Sentence examples for mutation based on from inspiring English sources

For instance, if strong positive selection fixes a mutation based on one aspect of the protein's function, but that mutation also has lesser, deleterious effects on other aspects of the protein's function, then natural selection will favor subsequent mutations that ameliorate these antagonistic effects.

Inclusion of an estimate of mutation based on a sample size of one should be clearly inadequate to anybody including Amos!

However, the remaining clinically diagnosed CINCA/NOMID patients (∼40%) show no heterozygous germline NLRP3 mutation based on conventional DNA sequencing-based genetic analyses (mutation-negative patients).

I had already published a prediction concerning the consequences of the mose likely mutation based on the same appraisal of the molecular control of heredity.

There are limited data on the probability of testing positive for genetic mutation based on clinical presentation.

It must be noted that the sample – of only 44 young people – specifically incorporated those with a high risk of the mutation based on their family history, and so can't be extrapolated to the general population.

Next, we were interested what the improvements were for different types of mutations based on the secondary structure and accessible surface area of the mutated residue.

Elemento's lab is building a database of important cancer genome mutations based on both their own data and the cancer research community's discoveries at large.

We built a panel of resistance mutations based on the Hain and AID line-probe assays, with a small number of additional mutations from the literature (see Methods section for details).

In this case, we compare the proposed mutation against classical Evolutionary Programming approaches, with mutations based on Gaussian, Cauchy and chaotic maps.

Using automated DNA sequencing, we tested individuals for BRCA mutations, based on positive family history of either breast or ovarian cancer or both.