Sentence examples for mutation at high from inspiring English sources

Selection for leanness in domesticated pigs created an overdominant situation maintaining the mutation at high frequency until a DNA based diagnostic became available that enabled the targeted culling of individuals bearing the Halothane mutation [16].

In conclusion, we report one of the largest studies in women with a proven mutation at high risk of hereditary ovarian cancer in a single institutional setting.

Consistent with previously reported frequencies [ 22- 25] these patients harbor this known driver mutation at high VAFs that are in the range of most other phylogenetically informative variants.

This method allowed us to measure mutation frequencies as low as 10−6, which is lower than that obtained with the only other published method to measure the ACH mutation at high sensitivity (13).

The mutants are generated through a mechanism that introduces point mutations at high rate into rearranged variable (V) region genes in the course of cell proliferation.

However, they will cause damages including protein carbolynation, lipid peroxidation, and DNA mutations at high levels, which contribute to disruptions of cellular homeostasis (Dan Dunn et al., 2015).

The mouse tumors contained activating NOTCH mutations at high frequency.

Our results are similar to a previous study by Kelliher and coworkers [25] using TAL1 transgenic mice, which acquire NOTCH1 mutations at high frequency.