Sentence examples for mutation at exon from inspiring English sources

For 23 patients only EGFR mutational analysis was possible, and only one patient (4%) harboured a mutation at exon 21.

The G608G mutation at exon 11 was introduced using the GeneTailor Site-Directed Mutagenesis System (Invitrogen).

On the other hand, Asn655Thr mutation at exon 13 of the c-kit gene was observed as a secondary mutation in case 2 with secondary resistance to nilotinib.

Kinoshita et al. reported that Asn655Lys mutation at exon 13 which was observed as a primary mutation in a sporadic GIST was imatinib-sensitive [31].

c This case has also TP53 mutation at exon 6, codon 217 (deletion1).

a http://www.1000genomes.org/ensembl-browser. b This case has also TP53 mutation at exon 6, codon 211 (G C>A T).

Of the 254 oral cavity OSCCs, 128 (50.4%) showed a p53 gene mutation at exons 4 10.

With the aim to ascertain the variety of mutations at exon 8, 9, 11, 13, 15 and17 of c-kit gene in breast cancer, we have done PCR-SSCP followed by DNA sequencing.

Therefore, we analyzed bone marrow aspirates from 35 adult patients with T-ALL for the presence of IL7R mutations at exon 6. IL7R insertion mutation was not detected in any of these cases.

The IL7R insertion mutations at exon 6 were detected in both childhood T-ALL and B-ALL, whereas a recurrent serine-to-cysteine substitution at amino acid 185 (the S185C mutation in the IL7R extracellular domain) was identified exclusively in childhood B-ALL.

The point mutation detected at exon 9 in five cases is Asp496Val.