Sentence examples for mutation at dna from inspiring English sources

At each evolutionary time-step, a new "trial sequence" is generated by random mutation, at DNA level, of the "current sequence" (accepted at the previous time-step).

Note that nonsynonymous substitutions (mutations) at DNA level are amino acid substitutions (mutations) at protein level.

Samples with LOH on 10q were analysed for PTEN and BMPR1A mutations at DNA and transcript levels.

Only SNPs causing missense mutations at DNA-contacting positions −1, 2, 3, and 6 or non-DNA-contacting positions C2, −2, 1, and 5 were retained for this study.

In addition to the G6PD variants from German ancestry described in Figure 1, a number of other variants have been described in the past, though without knowledge of the exact mutation at the DNA level.

What made some sites apparently prone to mutation at the DNA level whereas other sites still depend on a change at the RNA level?

Double-strand breaks (DSBs) at specific genomic sites can introduce a mutation at the DNA break site via the error-prone non-homologous end-joining (NHEJ) pathway.

This variant encodes a C629T (ccg to ctg) mutation at the DNA level and a Phenylalanine to Leucine change at amino acid residue 210 out of 1123 and this variant occurred in all 76 reads covering this position.

We also show that the specificity of these peptides can be improved by mutation at the DNA level that has implications for phenotyping and the development of Site Directed Assays.

Selection for BLUP or segregation analysis breeding value estimates both need 1 2 generations more to halve the frequency of the disease allele, while these methods do not require knowledge of the disease mutation at the DNA level.

Consequently, it is natural to handle frameshift mutations at the DNA level, by DNA sequence comparisons.