Sentence examples for mutation as is from inspiring English sources

We treat each amino acid substitution as if it can be acquired by a single-nucleotide mutation, as is the case for the circulating viruses closest to acquiring the Herfst et al. or Imai et al. sets [see (6) for the general case].

Although the significance of these events is not clear, it is expected that such loci may harbour genes in which the remaining allele may harbour a point mutation, as is the case for TP53.

However, it is also affected by the Zfhx3 Sci mutation, as is the period of the TTFL, as reported by PER expression.

Isoniazid resistance was most commonly associated with katG S315T1 mutation, as is the case in many high TB burden countries, presumably related to ongoing transmission of these strains [ 12].

Since the patient-specific iPSC-CMs should harbour the same disease-causing mutation as is present in the host tissue (skin fibroblasts or hair follicle), researchers could in theory reproduce the clinical phenotype 'in the petri dish' and thus establish an in vitro model of the disease.

Equally, adaptation did not start from a single new mutation as is expected from a hard sweep; these findings are also more consistent with soft sweeps where more than a single copy of the allele contributes to an adaptive substitution (Hermisson and Pennings 2005; Pennings and Hermisson 2006).

Around 5percentt of breast cancer cases are attributed to having inherited the BRCA gene mutation, as are 10 to 15percentt of cases of ovarian cancer, according to the Mayo Clinic.

The family members of LRRK2 PD patients were screened specifically for the G2019S mutation, as were the healthy control subjects.

Her unaffected brother was heterozygous for the A297V mutation as was her father.

While these mutation screening studies may be largely correlative, several experiments have helped establish the p300/CBP mutation as being causative.

Furthermore, this novel CHM mutation was detected in none of 200 healthy controls, which excluded the mutation as being a rare DNA polymorphism.