Sentence examples for mutation as identified from inspiring English sources

We also characterized a WT sibling (WT-sib) derived from a backcross of a heterozygous line for the bZIP1 T-DNA mutation, as identified by PCR analysis on genomic DNA.

The most common nevirapine-associated HIV drug resistance mutations were K103N, Y181C and G190A.> -wrap-foot> NNRTI = non-nucleoside reverse transcriptase inhibitor, NRTI = nucleoside reverse transcriptase inhibitor, DRM = drug resistance mutation (as identified Stanford Genotypic Resistance Interpretation Algorithm), ND = no data available.

The deviation from randomness is presence of a small excess of base changes closer than predicted, which are presumably due to clustered mutations, as identified by Drake [64].

29 The number of baseline primary PI mutations, as identified by the IAS-USA had minimal effect on virologic outcomes, as patients with 0 mutations in the TITAN trial achieved suppression in 84% (139/165) as did patients with ≥3 baseline mutations.

To examine the single nucleotide polymorphism (SNP) heterogeneity, a SNP was defined as a position with >20× Illumina MiSeq coverage that had SNPs supported by >3 reads that reflected substitution mutations as identified by SAMTOOLS and no indication of the presence of an insertion or deletion (indel).

A nonsense mutation in RAD51C was identified in another individual (UTSW13) who was originally tested in the clinic for an FH mutation (WGS identified this mutation as well).

Thousands of known disease-causing mutations are identified as well as new disease-linked genes.

This method correctly identified all 10 samples that were 3243A>G mutation-positive, all 4 samples that were 8344A>G mutation-positive, and all 30 samples that were negative for both mutations, as previously identified by traditional gel-based methods.

The RA tissue samples had five transition mutations (four A>G, one C>T) and one transversion mutation (G>T), with four mutations identified as missense and two as silent.

A fifth point mutation was identified in AS-30CQ, as predicted, on chr07.

As the c.1934dupG ASXL1 mutation was identified as one of transcripts resistant to nonsense-mediated decay in CRC with MSI, the ASXL1 mutant protein derived from the c.1934dupG allele is predicted to be expressed as a C-terminally truncated protein.