Sentence examples for mutation as an from inspiring English sources

Chou et al using mutational screening of primary AML patients demonstrated TET2 mutation as an unfavorable prognostic factor in AML with intermediate cytogenetics [ 73].

We present a familial breast cancer case with a BRCA1 mutation as an example.

Knapsack problem [17] has been proposed with a lot of mutation as an optimization model a long time ago, one of which is the multi-knapsack problem.

Interestingly, this residue appears to be constitutively phosphorylated in human melanoma cells harboring BRAFV600E activating mutation as an indicator of the connection between RAS pathway and LKB1.

In order to use mtDNA mutation as an unbiased tool for detection of clonal cell populations, sequencing of the entire mitochondrial genome is necessary and must be done together with an appropriate non-neoplastic control because of the highly polymorphic nature of the mtDNA [7].

We elected to use the Ser146 mutation as an insertion control as Ser146 is located outside of domain 1 and 3a and thus would not be predicted to affect syntaxin interactions (either to closed-conformation syntaxin or the N-terminus) and this was supported by our results as no effects on binding or exocytosis were demonstrated.

(Of the women who carry a BRCA1 mutation, as many as 85percentt will eventually develop breast cancer, and as many as 50percentt will develop ovarian cancer).

However, mutations as small as a single base (these are A, T, C, G) in your DNA can lead to life-altering diseases such as sickle cell anemia or cystic fibrosis.

Cal's 5-Alpha-reductase deficiency syndrome was caused by a recessive genetic mutation as a result of inbreeding.

The second mouse had been bred with a specific genetic mutation, as a consequence of which it could hear nothing and had no sense of balance.

In particular, the drug treated one type of dog cancer with the same genetic mutation as a human stomach tumor, she said.