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Exact(13)
Waddington's idea was based on the intuition that environmental change, stochastic variation, and mutation are likely to have similar effects on an organism, because they act through the same underlying molecular processes [21], [22], [23].
Thus, the c.1129 5923C>G mutation and c.1236G>A (p.E412E) mutation are likely to be in cis.
However, it is expected that MDR M. tuberculosis isolates with a KatG gene mutation are likely to be clustered [ 28].
The phenotypic effects of any given mutation are likely to be modified, perhaps strongly, by genetic background.
Therefore, genes which have undergone a nondeleterious frame shift mutation are likely expressed and can immediately contribute to an organism's phenotype.
As the St AOP2-1 allele does not contain the 5 bp deletion, mechanisms other than mRNA instability arising from a frame shift mutation are likely to be responsible for the lack of AOP2 expression in St.
Similar(47)
Whether such a mutation is likely anytime soon is unknown.
By contrast, I argue that germline mutation is likely to be a very weak balancing force in evolutionary dynamics.
In addition, since an allele of qSH1 is found only in the temperate japonica subspecies, this natural mutation is likely to have been selected during the domestication of japonica rice [16].
Since the selected sh4 allele was found in all examined landraces and modern cultivars of both indica and japonica rice, the sh4 mutation is likely to have been utilized during the very early stages of the rice domestication process.
Introduction of a longer side chain at position 665 by the L665F mutation is likely to generate hydrophobic interactions with the side chains of some of the above-mentioned residues.
More suggestions(14)
transfers are likely
mutation are reported
mutation are estimated
mutation are identified
mutation are expected
mutation are heterozygous
mutation are dominant
mutation are cross-resistant
mutation are immune
mutation are highlighted
mutation are unclear
mutation are low
mutation are tRNALeu UUR
mutation are indispensable
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Justyna Jupowicz-Kozak
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