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The genetic operators, crossover and mutation, are defined based on information gained about the feasible region and the behaviour of the objective function through the use of a data analysis procedure.
Thus four functional types of mutation are defined with respect to codons (synonymous Ts, synonymous Tv, nonsynonymous Ts, and nonsynonymous Tv).
The possibilities for ongoing mutation are defined through genetic interactions, and this fact is at the heart of the evolutionary process.
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A dominant mutation is defined here as one mutated residue containing the largest sequence count compared with other residues at a particular aligned position.
Unlike the undefined and leaky panD2 mutation, the panD S25A mutation is defined and tight.
Mutation is defined as a sudden change that occurs in the genes of the offspring when compared to that of parent genes during the evolution process.
Another kind of DNA mutation is defined as "copy number variation".
A back mutation is defined as a mutation which increases the fitness of a genotype as in [ 8].
While a mutation is defined as 'any change in the DNA', most work has focused on studying 'Single Nucleotide Variations' (SNVs).
A mutation is defined as a permanent change in the nucleotide sequence, while a polymorphism is defined as a variant with a frequency above 1%.
For samples recruited through EMBRACE, a pathogenic mutation was defined as an established disease-causing mutation under the classification scheme used by Breast Cancer Information Core.
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