Sentence examples for mutation are capable from inspiring English sources
Strains reconstructed with just the citT duplication and this dctA* mutation are capable of fully utilizing citrate (i.e., they are Cit++).
As mutation is capable of introducing diversity in the search procedure, two types of mutation have attracted the researchers - mutation of global best and mutation based on sharing information from neighbors.
In the case of Pro91, a single point mutation is capable of strongly slowing down the conformational diffusion along the denaturation coordinate, becoming a barrier-free downhill process above 371 K.
Reverse transcriptase containing the conservative K65R mutation was capable of limited phosphorolysis, however the nonconservative K65A and K65Q mutations abolished the activity (Fig. 5).
On the other hand, bevirimat-resistant SP1-A1V mutation was capable of rendering viruses resistant to PF-46496.
These functional assays demonstrate that the mutation is capable of inducing the intracellular production of the second messenger cGMP, which results in intestinal secretion through CFTR.
Despite their negative effects on fitness, deleterious mutations are capable of drifting to fixation in small populations [5] [9].
Like agonists or inverse agonists, activating or inactivating mutations are capable of shifting the equilibrium toward active and inactive conformations, respectively.
Second, that multiple mutations are capable of producing unexpected changes in cellular physiology by connecting previously unrelated pathways to produce new circuits.
Given that these EGFR mutations are capable of activating AKT (PMID: 15731348), these data suggest that the mechanism of PI3K activation (e.g. EGFR activation vs MET activation) is likely critical in establishing AKT dependence.
From this perspective, oncogenic mutations are capable of driving somatic evolution upon their occurrence, and their occurrence thus determines the timing of a multi-stage process of selection for pre-malignant clones, eventually leading to cancer.
