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Second, the impact of recurrent mutation appears most acute in closely related haplotypes, due to the low level of evolutionary signal (unique mutations that mark lineages) relative to evolutionary noise (recurrent, shared mutation in unrelated haplotypes).
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Identify the number that appears most often.
First, of the beneficial mutations that appear, most have small effects on fitness.
Mutation appears to be the most common mechanism by which PTPRs are genetically modified when compared with copy number amplification or loss.
Current diagnostic platforms generally assume that actionable 'driver' mutations are those appearing most frequently in cancer.
The genetic mutation appears to be rare.
This mutation appears to be tissue limited.
In addition, for fluctuating environments, fluctuations of intermediate frequency appear most favorable for elevating mutation rate (Travis and Travis 2002; Palmer and Lipsitch 2006).
Pancreatic cancers appear most frequently in families with MSH2 mutations, followed by MLH1 and MSH6.
A mutation in the BMP4 coding region resulting in an amino acid exchange (p.Arg300Pro) appeared most interesting among the identified variants.
Of the other 5, the gsiB mutation appeared to contribute the most (an additional threefold) when combined with the DNA repair function mutations.
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