Sentence examples for mutation appearing in from inspiring English sources

The FLT3 gene is one of the most commonly mutated genes in AML with the FLT3-ITD mutation appearing in roughly 24% of cases and being associated with a poor prognosis [ 46, 47].

Thus a beneficial mutation appearing in one chromosome, and helping the cell to divide faster might not get into one of the daughter cells.

In this case, we may simply assume that mut  =  ed, and interpret any such a mutation appearing in a script as being implem ented by the corresponding series of operations.

In the case of chronic HBV infection, prolonged lamivudine therapy exceeding 6 months in duration has been associated with an increased likelihood of treatment-emergent HBV variants with a YMDD mutation, appearing in 12 20% in the first year of treatment (Lau et al, 2003; Yeo et al, 2004b).

Theoretical work [ 5] shows that this definition of T scales the mutation rate per generation (U) to the neutral substitution rate (K) per time unit with a simple equation 1.1 Note that U by itself determines the probability of a new mutation appearing in an offspring [ 4, 6], and therefore lacks a timescale.

By Michael Specter July 11 , 2012For many years, when the term "rare gene mutation" appeared in a sentence along with "Alzheimer's disease," the news was reliably grim.

Conclusions: Although a known resistant mutation appeared in a renal transplant patient, it was not associated with CMV disease.

Among Spanish pedigrees, the 1555A>G mutation resided at the mtDNA haplogroups H, I, J, K, T, U, V and L, and a strong excess of haplogroups H3 mtDNA carrying the 1555A>G mutation appeared in these families (Achilli et al., 2004).

As an example of the research and evolution in lung cancer, within 10 years of the first TKI use in clinical practice, a new mutation appeared in far higher proportions in treated patients, T790, a mutation that makes them non-responsive to first and second generation TKIs [13].

This founder mutation appeared in all single cell clones and thus most likely it originated before we started this experiment.

The results showed that no mutation appeared in the siM2 targeting region even after 40 passages of the cultures (Fig. 6).