Sentence examples for mutation appeared in from inspiring English sources

By Michael Specter July 11 , 2012For many years, when the term "rare gene mutation" appeared in a sentence along with "Alzheimer's disease," the news was reliably grim.

Conclusions: Although a known resistant mutation appeared in a renal transplant patient, it was not associated with CMV disease.

Among Spanish pedigrees, the 1555A>G mutation resided at the mtDNA haplogroups H, I, J, K, T, U, V and L, and a strong excess of haplogroups H3 mtDNA carrying the 1555A>G mutation appeared in these families (Achilli et al., 2004).

As an example of the research and evolution in lung cancer, within 10 years of the first TKI use in clinical practice, a new mutation appeared in far higher proportions in treated patients, T790, a mutation that makes them non-responsive to first and second generation TKIs [13].

This founder mutation appeared in all single cell clones and thus most likely it originated before we started this experiment.

The results showed that no mutation appeared in the siM2 targeting region even after 40 passages of the cultures (Fig. 6).

The FLT3 gene is one of the most commonly mutated genes in AML with the FLT3-ITD mutation appearing in roughly 24% of cases and being associated with a poor prognosis [ 46, 47].

The V600E B-RAF mutation appears in 4%15%% of CRC.

The mutation appears in the region between but not within the two nuclear localization signal sequences.

Indeed, the HbS mutation appears in Africa on four different genetic backgrounds unrelated to each other by simple meiotic recombination events, whereas the HbE mutation appears in south-east Asia on at least two such backgrounds (reviewed in [ 231]).

Dideoxysequencing confirms that this mutation appears in AS-30CQ and AS-15MF but not in AS-ATN.