Sentence examples for mutation and was from inspiring English sources

It is notable that the post-AI ESR1-mutated tumour with the lowest oestrogen-regulated expression carried an E380Q mutation and was also HER2-positive though this is the only ESR1-mutated sample with HER2 overexpression making the importance of its association with low ERG expression uncertain.

A molecular diagnosis test was designed to detect this mutation and was used to show that it is still present in Cyprus Island.

Schrul, who had never smoked, was still processing this shocking news when his New Jersey doctor told him there was "good news:" He had the EGFR mutation and was therefore a candidate for targeted therapy instead of traditional chemo.

The IMPACT study (Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted screening in men at higher genetic risk and controls; www.impact-study.co.uk) is an international multi-centre study evaluating the role of targeted PSA screening in men with a BRCA1 or BRCA2 mutation and was established in 2005 (Bancroft et al, 2014).

The tests revealed she had an EGFR mutation and was able to go on a targeted therapy.

Because I carry the BRCA2 genetic mutation and was at a statistically higher risk for ovarian cancer, I chose to to have prophylactic surgery to remove my ovaries and fallopian tubes.

Thirty-nine patients had H63D mutation and were all heterozygous.

Additionally, it induces DNA mutation and is carcinogenic to humans.

Because this disease is autosomal recessive, parents can carry the genetic mutations and be completely healthy.

Their genes can undergo random mutations and be turned on and off by things in their environment.

Mutations that confer a fitness advantage to the cell are known as driver mutations and are causally related to tumorigenesis.