Sentence examples for mutation and two from inspiring English sources

Four individuals with severe POAG were found to have novel missense mutations in exon 3. Two exhibit an Asp380Asn mutation and two an Arg342Lys mutation.

To this end, four different human NSCLC cell lines were employed, two of which express the commonly encountered mutations in the EGFR TK domain (delE746-A750 mutandon and L858R point mutation) and two additional lines expressing the secondary T790M mutation or wild-type EGFR (wtEGFR).

One pathogenic BRCA1 mutation and two novel pathogenic BRCA2 mutations were detected in two of 37 index cases.

kismet (kis): We tested three mutations of the kis locus, a point mutation and two small deficiencies, and all three suppress TPE (Table 5).

In addition, our observation that a dcl2 null mutation and two viral suppressors of silencing have the same effect on secondary siRNA accumulation suggests that natural substrates of DCL2 might be produced in viral infection.

One of these clones had one nucleotide polymorphism in the sequence overlapping with one of the primers used for amplification (mutation derived from the primer and not the cloning strategy), one clone had a PCR-induced mutation, and two clones had the correct sequence.

One of them carries a BHD mutation and eight of them have TP53 mutations (72.7% of TP53-mutated chromophobe; P<0.02).

To further improve the activity, the F124W mutation and three previously reported beneficial mutations were combined randomly into double and triple mutants.

Four additional patients carried one missense mutation and one insertion or deletion mutation, and the missense mutations in these four patients were accurately detected.

Five multiplets (71%, 5/7) reside in the same exon or two exons, consistent with one mutation and one chronocoordinate doublet.

We tested one point mutation and one deficiency for the locus and found both were moderate Su TPE s (Table 1).