Sentence examples for mutation and thus from inspiring English sources
These endogenous mutagens are known to generate certain subclasses of mutation and, thus, also might shape mutational catalogs within cancer genomes (Ames and Gold, 1991).
Using this model, you might expect that larger organisms would undergo more gene mutation, and thus be more prone to cancer.
Large phage populations were used in order to maximize the amount of sequence space explored by mutation, and thus the potential for parallel evolution.
These, too, showed more tropical than temperate mutations.By a process of elimination, therefore, the three researchers were left with the conclusion that, by pushing metabolic rates up, tropical heat causes more mutation and thus more speciation.
It is known that even if a ligand peptide is designed to bind to a target receptor on the surface of a pathogen such as viruses, bacteria or cancer cells, it is likely that some receptors are subject to random mutation and thus the ligand has a reduced ability to bind to these receptors.
It is similar to the heuristic mutation and thus lacks the interchange of characteristics between chromosomes.
Three NSCLC cell lines were selected for the generation of xenografts and the in vivo evaluation of [11C]erlotinib and [18F]afatinib, each expressing a specific EGFR mutation and thus providing a representative overview of mutations found in clinical cases of NSCLC [24].
Mutational heteroplasmy appears to be generally more common than complete mutations and thus a more sensitive means of detecting increased mutation rates in populations.
In 16% of the cases, the mutations were either frameshift- or nonsense-mutations, and thus functional consequences were apparent.
Children's cancers, however, generally have far fewer mutations and thus may offer fewer targets, according to one theory.
Together, the study of these different mutational strands — the good, the bad and the irrelevant — is weaving a comprehensive picture of the general distribution of mutations, and thus, the spectrum of genetic variation that appears in nature.
