Sentence examples for mutation and reduced from inspiring English sources

The BoxG1 mutation and reduced expression of glmUS may thus confer an advantage by reducing excess synthesis of these components.

Thus, the synergistic effect between an ndg-4 mutation and reduced insulin signaling is consistent with altered lipid signaling being responsible for the longevity.

The co-existence of TP53 mutation and reduced levels of a series of lipid glycerophosphocholines was the most significant association detected.

In a related report, Cbl mutation and reduced EGFR ubiquitination inhibited early endosome fusion and EGFR degradation in HEK 293 cells [ 20].

Ectopic expression of RAD51 in a PTEN-deficient cell line was also able to overcome PARP inhibitor sensitivity, supporting the proposed link between PTEN mutation and reduced RAD51 expression.

Indeed, similar phenotypes to those observed in this study have been found by Hoffman et al. [ 32] who showed, using a MSH2 T-DNA insertion mutant, that disabling the MMR system in Arabidopsis leads to high levels of mutation and reduced fertility within two generations in some lines.

The flavonoid pigments present in a wide range of plant products are considered to have antioxidant effects that inhibit cell mutation and reduce chemically induced colorectal carcinogenesis, but they may also prevent diabetes [ 8– 10].

In this study, we observed an overall association between BRCA1/2 mutations and reduced life expectancy after excluding deaths following diagnosis of the cancers that have been shown to be related to these mutations.

Now many of techniques are used in diagnosing the biological and clinical differences of leukemic cells, including the acquisition of new chromosomal abnormalities, gene mutations, and reduced responsiveness to chemotherapeutic agents [10] [13].

The interaction of Kapβ2 with RAM was inhibited by the PY1AA or PY1/2AA mutations and reduced by the PY2AA mutation.

Consequent selection of cells with mutations and reduced radiosensitivity can lead to disease progression and treatment-resistance.