Sentence examples for mutation and onset from inspiring English sources

There appears to be no correlation between type or location of the Gs-alpha mutation, and onset of the disease, severity of endocrine resistances, or number of AHO signs in PHP1a/PPHP [Elli et al., 2013b].

The researchers, from the United States and Canada, said a double mastectomy should be discussed as an option for young women with a BRCA mutation and early onset breast cancer.

The linkage between the mutation and the onset of cataract was also characterized by the prominent effects of the p.Trp43Arg mutation on γD-crystallin structure and stability.

Finally, we found no obvious correlation between the magnitude of change in charge by mutation and disease onset or duration (see Supplementary Material, Fig. S2).

The consistency among investigations on oncogene/tumor-suppressor gene mutations in lung cancer (and other tobacco-related cancers) in smokers is highly suggestive, although we still lack information about the time sequence between exposure, gene mutation, and cancer onset.

17 CpG island methylator phenotype‐positive CRC is reportedly associated with a higher ratio of tumors with the BRAF mutation and disease onset in women, the elderly, and patients with a history of smoking.

Our patients with Phe100Val mutation and distal-onset myopathy have a range of ages of onset (10 to 50) and severity, as mentioned.

The only other cases with a missense mutation and distal-onset myopathy (Pro96Arg) had a range of age of onset from 18 to 35.

One has a Phe100Val mutation and distal-onset myopathy, unique early bulbar involvement, and a gender-modified wide age-of-onset range.

Intriguingly, we find that there are several mutation signatures at play in many of these patients, contributing varying proportions of mutations and with onset at different times during cancer evolution.

One has the known Phe93Leu mutation and classic late-onset slowly progressive LGMD1D.