Sentence examples for mutation and none from inspiring English sources

Twenty-one are homozygous for the common c.C826A missense mutation, and none has known brain dysfunction or malformation.

Comparing the drug with a known chemotherapy agent, the team found that after 72 hours, AG1295 had killed nearly half the cancer cells that contained a FLT3 mutation and none of the cells that did not, while the chemotherapy agent killed cells with or without FLT3 mutations with equal vigor.

PI3K-pathway activation rarely occurred through point mutation of PTEN or PIK3CA in this dataset: exon-resequencing of 80 tumors revealed only 2 tumors with PIK3CA mutation and none with PTEN mutation [30].

History of cancer in the families negative for the R337H mutation, presented LFL only in one family with CPC without the R337H mutation and none in families with Pp.

The non-Ashkenazis were also analysed for the Tyr978X BRCA1 mutation, and none was a carrier.

The sister (III:3) of the index patient and one niece (IV:5) were tested for the familial MSH6 mutation and none of them carries the mutation.

We also explored mechanisms of acquired PARPi resistance by screening post-rucaparib treated PDX samples for the presence of reversion or secondary BRCA1/2 mutations and none were observed.

A few months later, Kim stumbled across a new paper by a team of British researchers who had studied 108 people with ARVC and found that four had LMNA mutations (and none of the standard ones).

The microarray was able to detect 22 of the missense mutations and none of the insertion or deletion mutations (Table S2).

Moreover, screening for MSH2 and MLH1 mutations in 77 cases of familial ovarian cancer, who previously tested negative for BRCA1 and BRCA2 mutations, revealed 2 cases with MSH2 mutations and none with a MLH1 mutation [20].

All the patients included in this study were tested for known PD-related mutations and none of the patients with idiopathic PD were found to have any such mutations.