Sentence examples for mutation and low from inspiring English sources

In the multivariate analysis, KRAS (HR 4.3, p<0.0001), BRAF (HR 5.1, p<0.0001) mutation and low EREG mRNA expression (HR 1.6, p = 0.021) emerged as independent factors associated with reduced TTP.

In addition, KRAS (HR 2.9, p = 0.01), BRAF (HR 3.0, p = 0.001) mutation and low EREG mRNA expression (HR 1.7, p = 0.021) emerged as independent factors associated with reduced OS.

CIMP-high CRC significantly correlates to microsatellite instability, BRAF mutation and low TP53 mutation rate, while CIMP-low tumors present a higher rate of KRAS mutation [ 6].

A similar approach was not employed with mm due to variable expressivity of the mutation and low recombination rate in the region.

LOH mutations were defined as high clonality when >75% of the DNA had LOH mutation and low clonality when 50-75% of the DNA had LOH mutation.

LOH mutations were high clonality when greater than 75% of the DNA had LOH mutation, and low clonality when 50 75% of the DNA had LOH mutation.

In this study, high-susceptible strains of E. coli lacking a QRDR mutation and low-susceptible strains with one QRDR mutation were used as original strains.

On a molecular level, mutator mice accumulate extremely high levels of mtDNA point mutations and low levels of multiple mtDNA deletions (28, 55, 56).

The study revealed many off-target effects (random introduction of mutations) and low efficiency levels for introduction of the corrective gene they were using.

However, the presence of drug resistance mutations and low level viraemia among clinically asymptomatic patients highlights the need for virological monitoring.

At present, we do not know the nature of these mechanisms, but fixation of deleterious mutations and low genetic diversity resulting from repeated population bottlenecks are likely candidates.