Sentence examples for mutation and little from inspiring English sources

"A cell acquired a mutation, and little by little it acquired more and more mutations.

The low frequency of recurrent mutations and the little overlap of mutated genes (except EGFR) across the studies may suggest the mutational drivers for lung cancer in never smokers can be diverse and highly individualized.

These new roles for ATM and TP53 that are unrelated to their DNA damage response functions may help to explain how mutations in these genes are advantageous for CLL cells despite the very low rates of somatic mutation in CLL and little evidence of clonal selection pre-treatment.

This is the first key takeaway: everything is subject to an unceasing mutation and we have little influence on this natural process.

A majority of mutations, however, are like the U39A mutation and have very little effect on the suboptimal ensemble.

The GHR-KO mutation was associated with much smaller transcriptional effects than mutations carried by Snell, Ames and Little mice.

23, 24 Synonymous base pair mutations implied little phenotypic change and little or no selective pressure on the haplotypes.

These data indicate that little natural mutation and modification in the TAC1 coding region occurred within the cultivated rice and its progenitor during evolution.

The H64A mutation showed little effect, whereas H64Q and H64W caused increases of 56 and 65 mV, respectively.

Animal mt genomes are generally small, compact, and exhibit high mutation rates, whereas plant mt genomes exhibit low mutation rates, little compactness, larger sizes, and highly rearranged structures.

Taken together, our data shows that the JH2 domain reduces the affinity for ATP and that the V617F mutation has little or no effect on this parameter.