Sentence examples for mutation and increase from inspiring English sources

Because this research worked on an individual genome of mutants, another strategy has been developed to sequence pooled DNA from different mutants to remove the effect of background mutation and increase the likelihood of identifying the causative gene.

The presence of HCC was associated with the double mutation and increased age.

The persistent oxidative stress causes DNA mutation and increases fibroblastic activity, leading to liver cirrhosis and carcinoma.

Interestingly, a recent publication has cited an association between BRCA1 mutation and increased progesterone receptor signalling (Ma et al, 2006).

Furthermore, the age-dependent V(D J selection coincides with the progressive introduction of IgVH mutation and increased class-switch.

Under 2.0% glucose conditions, the RLS of the fob1Δ cells was decreased by the sir2-S473E mutandon and increased by the sir2-S473A mutation.

Therefore, adjustment threshold for calling a mutation and increasing the read depth in samples is required for each gene and can improve consistency.

These findings were consistent with the lack of association observed between the BRAF mutation and increased risk of recurrence or cancer-related mortality on univariate and multivariate analyses.

Here we report a large study of nearly 2000 PrCa cases with varying ages of diagnosis to validate the potential association between germline BRCA2 mutation and increased risk of disease and to refine RR for PrCa among BRCA2 mutation carriers.

These mutations may help to enrich the GALC pathogenic mutation database and increase public awareness of Krabbe disease in Morocco.

However, we recognize that our summary may not contain all Nav channel disease-related mutations owing to abundant literatures reporting Nav channel disease-related mutations and increasing volume of work describing new findings.