Sentence examples for mutation and identification from inspiring English sources

Han et al reported that only 18.1% of patients with p-Erk positive tumors harbored K-ras gene mutation, and identification of other molecular mechanisms leading to p-Erk activation and gefitinib resistance was mandatory [ 18].

Research fields are diverse, including basic research on cell proliferation, analysis of tumour cells and tissues to detect gene mutations, and identification of potential therapeutic targets in cancer.

The need for software packages allowing combined analysis of viral evolution, detection of compensatory mutations, and identification of immune escape patterns is evident.

Yamane et al. (2011) reported about deep sequencing analysis of mutations and identification of the genomic targets of AID in mouse B-cells and provided the evidences of association of ssDNA hypermutation sites with APOBEC binding motif.

Since contamination of DNA from out-crossing plants critically impacts on estimation of mutation density and identification of mutant, out-crossing plants was carefully examined by simple sequence repeat (SSR) analysis.

Mutation screening and identification of type of acute porphyria can be done at the quiescent phase of the disease.

This paper presents a method that allows rapid and easy visualization of mutation data sets and identification of potential gene mutation hotspot sites and/or regions.

The discovery of gene mutations and the identification of the cellular pathways that their encoded proteins control provide a wide range of new targets for drug development.

The high prevalence of the ras gene mutations and the identification of similar mutations in other models of c-Myc-induced mammary tumorigenesis suggest c-Myc overexpression may be causal in these mutagenic events.

Importantly, a fraction of NSCLC patients have displayed partial response to erlotinib despite lack of EGFR mutations and the identification of molecular biomarkers of response would be of great clinical value to prospectively select those EGFR-WT patients who are likely to benefit from erlotinib therapy.

Samples screening positive for potential mutations were selected for confirmation and identification of mutations by PCR amplification and sequencing using an ABI 3100 capillary sequencer (Applied Biosystems Inc., Foster City, CA, USA).