Sentence examples for mutation and have from inspiring English sources

DENVER, May 19 , 1997-Prophylacticmastectomy and oophorectomy (removal of the ovaries) for women who carry the BRCA1 mutation and have a family history of breast and ovarian cancer can prolong life expectancy by approximately 8.5 years, but at a great cost to quality of life, concludes a new study by researchers at Columbia-Presbyterian Medical Center.

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CIMF patients with the JAK2 V617F mutation are clinically distinct from those lacking JAK2 mutation, and have a worse overall prognosis [44].

In our first report [15], only one paternal aunt (Subject A-IV-23) was found to carry the mutation and have liver disease.

We have identified patients (Tables 1 & 2) with a history of MDS/MPD-U both positive (N = 12) and negative (N = 18) for the JAK2 V617F mutation and have analyzed them using 250K SNP-A.

These data appear consistent with (iv) above, rapid mutation, and have now been included.

In addition, all isolates carried the G2576T mutation and had 4 of 5 mutated alleles.

His mother, Eugenia Brin, also carries the gene mutation and has Parkinson's.

Patients who developed the codon 74 mutation had a greater decline in CD4+ T cells after the development of the mutation and had a greater serum virus burden than did patients without the codon 74 mutation.

There were eight diabetic subjects who did not carry the mutation and had type 2 diabetes.

Individuals 3 and 5 carry missense GRIN2B mutations and have a milder phenotype than the other three individuals.