Sentence examples for mutation and future from inspiring English sources

However, the astrocytic phenotype was observed in the H3.1-mutated tumours independently of the ACVR1 mutation and future work in vitro should help unravel this matter.

Although our data do not provide support for altered thymic selection being an explanation for the reduced T cell numbers in blt/blt mice, we cannot exclude the possibility that the selection of some T cell specificities is affected by the Zfp335 mutation and future deep sequencing studies will be needed to fully address this issue.

Where within this background of variation a given mutation (and future competing mutations) falls can slow down or speed up the spread of a given mutation and determine its ultimate fate (D esai and F isher 2007; P ark and K rug 2007; F ogle et al. 2008; P ark et al. 2010).

Finally, we discuss the potential functional implications of the mutation and suggest future prospects to evaluate the effect of the mutated CEP63 on cellular functions.

The father is heterozygous for the frameshift mutation and any future offspring will be at 50% risk of permanent neonatal diabetes.

This study provides an essential insight into the underlying molecular mechanism of Tyrp1 protein upon mutation and in future it may help to develop a personalized medicine for OCA3.

As a research tool, this will allow for greater manipulation of the genome while minimizing confounding mutations, and for future clinical applications, high targeting densities coupled with high-fidelity target recognition will be paramount to delivering safe and effective therapeutics.

Although greater improvements in overproduction of metabolites and antibiotics of specific microbes have resulted from essentially random empirical approaches to mutation and strain development, future strain development technology will be supplemented by more knowledge-based scientific methods.

We believe that this is a contribution to the few reports on the phenotype of this mutation and to the future elucidation of genotype-phenotype correlations of this disease.

NGS has also already been successfully used for detecting mutations in cancer genes, and future research is expected to identify more of these mutations, which might be of therapeutic value.

Although the two current hotbeds of musical Afrofuturism are LA (with the "beat scene" there headed up by Flying Lotus, whose aunt is Alice Coltrane, the second wife of John Coltrane and an important jazz artist in her own right) and Atlanta (which has its own mutations from OutKast, Monáe and Future), UK artists are also drawing on Afrofuturism for inspiration.