Sentence examples for mutation and epigenetic from inspiring English sources

It also examines compelling evidence that the underlying miRNA biogenesis machinery and miRNA genes themselves are subject to disease-associated genetic mutation and epigenetic influence.

The current perspective considers cancer as selection biased differential fitness between heterogeneous populations of clonal lineages that arises as a function of genetic mutation and epigenetic alterations [3].

To characterize the intrinsic features of an inter-module network, particularly the identification of 'gatekeeper modules', we further compared the rates of genetic (somatic mutation) and epigenetic (DNA methylation) aberration on tumor vs. normal tissues.

The present work is the first report evaluating RB1 mutation and epigenetic status in metastatic breast cancer.

The selection pressures and processes leading to differential mutation and epigenetic landscapes across tumor subgroups are however unknown.

Therefore, we examined the relationship between tobacco use, asbestos exposure and k-ras mutation, and epigenetic silencing of the BMPs (Table 2).

The pathogenesis of AML involves cytogenetic abnormalities, genetic mutations, and epigenetic anomalies.

Hsp90's vast interaction network explains the breadth of its phenotypic reach, including Hsp90-dependent de novo mutations and epigenetic effects on gene regulation.

We have discussed genomic mutations and epigenetic modifications in pediatric asthma and ASD.

Both ITH and IMH thrive on diversifying through mutations and epigenetic changes, which can be viewed as an individual ever-branching cancer tree.

Mutations and epigenetic aberrant signaling of growth factors pathways contribute to carcinogenesis.