Sentence examples for mutation and development from inspiring English sources

Identification of the causative mutation and development of a gene test enable such carrier animals to be excluded from breeding.

While there is significant correlation between BRCA1 mutation and development of breast cancer, it is still controversial whether or not there is a correlation between the presence of methylated BRCA1 promoter in WBC and paired tumor DNA from breast cancer patients [ 25].

While the causative genetic link between the Grey mutation and development of Grey horse melanoma is well established, the molecular mechanism behind this link remains uncharacterized as well as it is not known whether additional somatic mutations are required for tumourigenesis.

Recently, whole genome sequencing approaches in the haematopoietic system revealed an age-associated increase of mutations in human HSCs and provided insight into the clonal evolution of mutations and development of leukaemia (Busque et al., 2012; Corces-Zimmerman et al., 2014; Welch et al., 2012; Xie et al., 2014).

Although greater improvements in overproduction of metabolites and antibiotics of specific microbes have resulted from essentially random empirical approaches to mutation and strain development, future strain development technology will be supplemented by more knowledge-based scientific methods.

These offshoots include fusions with noise music, ambient music, folk music, post-punk and electronic dance music, as well as other mutations and developments.

This conception is not based on the "shifting gene frequencies" paradigm of the MS, but instead partakes of the mutationist view of evolution as a 2-step proposal-and-acceptance process whose kinetics depend directly on the introduction of novelty by mutation-and-altered-development.

We show that there is good correlation between the level of mitochondrial DNA mutation and the development of respiratory chain deficiency.

These results indicate that a sufficiently long time since first exposed to cigarette smoke is important in order to evaluate the association of smoking, APC mutation and CRC development.

Since the discovery of an association between a BRCA mutation and the development of fallopian tube cancer, bilateral oophorectomy has been extended to bilateral salpingo-oophorectomy (BSO) (Zweemer et al, 2000; Olivier et al, 2004).

More universally, Ghysen [107] argues that vertebrate as well as insect brains have ancient principle sensory and motor circuits with stable functions upon which alterations by gene mutations and embryonic development during evolution are applied to home new functions.