Sentence examples for mutation and control from inspiring English sources

Treatment with ambroxol also reduced the rate of dihydroethidium oxidation in Gaucher disease, Parkinson's disease with GBA mutation and control fibroblasts.

Conventional and real-time RT-PCRs were performed on patient blood-derived cDNA using primers spanning the exon 5 6 junction to compare AIP expression between patients carrying the mutation and control individuals.

To perform this competition assay, plates coated with BSA-FITC as above were incubated for 1h with an HRP-conjugated anti-FITC antibody pretreated for 2h with cell lysates of fibroblasts from APBD patients homozygous for the GBE p.Y329S mutation and control patients.

To characterize possible effects of LMNA mutations on lipid profile, we set out to apply global serum lipidomics using Ultra Performance Liquid Chromatography coupled to mass spectrometry in the same LMNA carriers, DCM patients without LMNA mutation and controls.

Positive (SW480 cell line) and negative controls (Human Placental DNA) for the mutation and controls for carryover DNA contamination were included in every experiment.

The non-energy linked activity of NNT was evaluated in mitochondria-enriched fractions from lymphocytes obtained from a 21 y old patient (carrying a homozygous F215S NNT mutation), his parents (heterozygous for this mutation) and controls.

Human skin fibroblasts established from skin biopsies taken from PD patients with G2019S LRRK2 mutation and controls (Supplementary Material, Table S2), with informed consent and ethical approval, were grown under standard conditions (58).

The performance of the software is affected by the number of predicted splicing mutations, the number of abnormal samples containing mutations and control samples and the corresponding RNA-Seq data for each type of sample.

We investigated a cohort of PSEN1 presymptomatic mutation carriers who were relatively close to their expected age at symptom onset, together with groups of symptomatic mutation carriers and control subjects.

Using the G2 assay, they found no difference in G2 chromosomal radiosensitivity between healthy BRCA1 mutation carriers and control individuals and they concluded that G2 radiosensitivity is no feature of individuals heterozygous for BRCA1 mutations.

Also, the performance of DCSaDE-LS is compared with the recent adaptive DE algorithms namely Ensemble of mutation strategies and control parameters in Differential Evolution (EPSDE), Composite Differential Evolution (CoDE) and SaDE.