Your English writing platform
Discover LudwigExact(3)
People who inherit only one dose of the mutation and become H.I.V.-infected often take about two years longer to develop AIDS than infected people without the mutation.
Both the early-stage tumours lacking persistent staining and those cancers with p53 staining may later undergo p53 mutation and become aggressive and invasive.
For the cells with two mutations there are also assumed to be competing processes of cell growth, differentiation, and mutation taking place at rates G(2)(t), D(2)(t), and M 2)(t), respectively, and so on until at the (k-1 th k-1 ththe cellstagech have accumulathe (k-1)mutations procellsat a rate M(k-1)(t) to acquire another mutation and become malignant.
Similar(57)
Specifically, it was reported that five patients (14%) with lung ADC were found to have a diagnosis of SCLC in EGFR TKI-resistant tumor biopsies despite maintaining the original mutation and became sensitive to classical SCLC treatment (Sequist et al., 2011).
These bottlenecks, called master regulators, integrate these mutations and become essential functional drivers of diseases such as cancer.
They then developed a model of viral evolution to test whether existing viruses, once they happen to infect a mammalian host, might accumulate the missing mutations and become excreted in respiratory droplets, which could start a chain of transmission.
Therefore, the H-strand tends to accumulate A→G and C→U mutations and become GT-rich while the L-strand tends to become AC-rich.
Conversely, if the influx of deleterious mutations were to overwhelm the purging process by preventing the production of offspring free of newly arisen deleterious mutations, then selfing organisms would be at risk of fixing increasing numbers of deleterious mutations and become subject to a mutation meltdown [21], [22].
Once integrated in the genome, TEs accumulate mutations and become transpositionally inactive.
Normal stem cells with inherent self-renewal capacity may acquire mutations and become transformed.
Additionally, upon environmental stresses, originally isogenic cooperators and cheaters can quickly acquire different mutations and become nonisogenic (Morgan et al., 2012; Waite and Shou, 2012).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com