Sentence examples for mutation and acquisition from inspiring English sources

This tends to lead to higher rates of both mutation and acquisition of DNA from other strains.

There are two important types of genetic mechanisms that can give rise to antibiotic resistance: mutation and acquisition of new genetic material.

Gram-negative bacteria develop resistance to commonly prescribed antibiotics through mutation and gene acquisition.

The EnCYP51 CNV and its allelic form did not correlate with SSR-based clustering suggesting that the Y136F mutation and the acquisition of multiple of copies of the EnCYP51 gene occurred multiple times in the E. necator populations screened.

Interestingly, preclinical investigations show that p53 mutations and the acquisition of cisplatin resistance are associated with increased sensitivity to taxanes in ovarian carcinoma cells (Cassinelli et al, 2001).

However, V. cholerae resistance to antimicrobial drugs is increasing because of the accumulation of genetic mutations and the acquisition of resistance genes, which are usually transferred on mobile genetic elements such as integrating conjugative elements (ICEs) (1 ).

Antibiotics are unique medications in that their targets (bacteria) are living organisms capable of adapting by developing mechanisms that confer resistance to antibiotics (e.g., mutations and the acquisition of resistance-gene vehicles).

Dan et al. [ 13] showed that a recently evolved overlap between MINK and CHRNE genes resulted from mutations in the polyadenlylation signal and acquisition of a new downstream signal within a neighboring locus.

Tumour cell heterogeneity within a given tumour may arise from clonal expansion and acquisition of mutations during tumour progression [ 21, 41] and/or under selective pressure (i.e. during therapy), favouring the survival of the best adapted clone with resistant properties.

This may suggest a correlation between genomic complexity and acquisition of p53 mutations and/or secondary RAS-activating mutations, however this is conjecture at this point.

Preneoplastic or neoplastic cells with a mutator phenotype will undergo the same successive rounds of mutation acquisition and clonal expansions as predicted by the first theory.