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We believe that the results from this genomic level study will be certainly helpful for the design of physiological studies and mutation analysis towards the verification of some hypotheses proposed in this study, which in turn will lead to a better understanding of signal transductions involved in the pathogenicities of mutans streptococci.
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Based on these findings, we propose that virtual screening and mutation analysis of BAX is found to be the critical advance method towards the discovery of novel anticancer therapeutics.
Table 2 Gene mutation analysis.
Mutation analysis was performed simultaneously.
Moreover, gene mutation analysis revealed that lesions acquired resistance via secondary KIT mutations in addition to primary KIT mutations.
Gene mutation analysis revealed a Del-5a.aDel-5a.a1) KIT mutation in exon 11.
In gene mutation analysis, a secondary KIT gene mutation was detected in one case.
Currently, EPCAM gene mutation analysis is not available in Japan.
According to gene mutation analysis, the resistant GIST contained the same genetic KIT mutation in exon 11 observed in the primary GIST without any secondary mutations.
Gene mutation analysis revealed a Lys (AAG) 558 to Asn&Pro (AACCCG) KIT mutation in exon 11.
The main outcome of the mutation analysis is the mutation score, which indicates the effectiveness of a test suite.
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