Sentence examples for mutation analysis tools from inspiring English sources

Perhaps the most important recent application of mutation analysis tools is in the realm of cancer research, where an influx of data regarding somatic mutations found in cancer emphasizes the need for efficient and reliable analysis methods [8] [14].

A brief summary of similarities and differences between homology searches and conservation analysis approaches implemented within evaluated mutation analysis tools is provided in Table 5. GeneSV is a computational system designed to facilitate assessment of regions of sequence variability in genomic sequences.

DoPloCompare: integrate into the RNAMute mutation analysis tool [ 16], which might be found beneficial in cases where dot plots are dealt with for visualization.

The RNAMute mutation analysis tool, [ 16], includes RNAdistance from [ 2, 6]: the RNA edit distance of the dot bracket representation as a fine-grain comparison method, and the edit distance of the Shapiro representation, [ 4, 5], as a coarse-grain comparison method.

Based on this concept, one may develop a mutation cluster analysis tool to identify the analogous mutation clusters between cancer and germline disease mutations.

The availability of a ZF model for PXE opens novel avenues for functional evaluation of ABCC6 mutations (see Molecular Analysis Tools) and for the screening of potential therapeutic compounds [ 66, 72, 73].

Therefore many in vitro and in vivo assays have been developed for MMR gene mutation analysis, using various molecular genetics tools [ 6- 16].

Resistance mutations were identified using resistance analysis tools available over the Internet.

Our data support the notion that screening for MSI in tumours is an efficient prescreening tool for mutation analysis.

To eliminate the bottleneck in mutation analysis, we need a bioinformatics tool that would enable us to readily evaluate the impact of a genetic variation on the structure/function of a gene product at the molecular level.

In summary, Mutation@A Glance provides a highly integrated bioinformatics tool for mutation analysis not only for facilitating visualization of sequence variation data along with various types of information, including primary and tertiary structures of the gene products, but also for evaluating the effects of novel sequence variations in a query input DNA sequence.