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Table 2 presents the mutation analysis results in the three experiments.
Fig. 9 Mutation analysis results of the b2llvm and C4B case study.
Table 2 Mutation analysis results Modules Experiment Percentage of mutants killed mutation score % Equivalent classes Boundary value analysis Logical Name Op.
VHL mutation analysis in the VHL patient cohort was performed by direct sequencing and MLPA analysis and the mutation analysis results have been reported previously [20].
100% concordance was achieved in the DNA mutation analysis results obtained between the two reference laboratories.
The conserved intermolecular correlated mutations are shown in Additional File 7. Based on the analyses described above we conclude that the correlated mutation analysis results clearly contain biological signal.
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Mutation analysis resulted in the identification of several nucleotide substitutions (Table 1).
Second, because only a relatively small number of patients received EGFR mutation analysis, the results of EGFR mutation and EGFR-TKI treatment in the young lung cancer patients should be interpreted carefully.
Mutation subtype analysis results in iTARGET and EURTAC were also similar to our study, with exon 19 deletions and L858R the most common mutation subtypes detected.
In conclusion, we describe the successful implementation of a scalable workflow solution that permits preappointment BRAF/KIT mutation analysis and result delivery in melanoma patients.
Sensitivity and specificity along with 95% confidence intervals (score method) were calculated for BRAF V600E IHC analysis based on the reading of the primary reviewer compared to the BRAF V600E mutation molecular analysis result considered the "gold standard".
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