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In many studies in lung cancer, but also in other cancers, EGFR mutation analysis has been restricted to the exons known to be frequently mutated.
Single-point mutation analysis has often resulted in perplexing results, which are difficult to simulate using computation.
To systematically evaluate how LATS1/2 genes play a critical role in human cancer, a mutation analysis has been carried out.
Despite its high specificity, our meta-analysis shows that BRAFV600E mutation analysis has a low sensitivity in diagnosing papillary thyroid cancer in thyroid nodules.
Correlated amino acid mutation analysis has been widely used to infer functional interactions between different sites in a protein.
Nonetheless, FBN1 mutation analysis has diagnostic limitations.
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A rapid and accurate technique for assessing galactocerebrosidase activity and performing DNA mutation analysis had been developed.
The methods for DNA isolation and mutation analysis have been described elsewhere.
Patients and mutation analysis have been described in Zhang et al. (2007).
The details of all the primers used for mutation analysis have been provided in Additional file 2: Table S7.
Most of the applications of IT for splicing mutation analysis have involved predominantly rare diseases, as well as some low frequency variants associated with more common genetic conditions.
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