Sentence examples for mutation analysis for from inspiring English sources

The above findings suggest that mutation analysis for the KRAS, NRAS, BRAF and PIK3CA genes should be implemented in molecular diagnostic laboratories.

Once this has been established, mutation analysis for the selection of patients for whom anti-EGFR therapy will be beneficial presumably has to be extended to KRAS exon 3, PIK3CA, BRAF and NRAS.

Somatic hotspot mutation analysis for KRAS, PIK3CA, BRAF and EGFR can reliably be performed using allele-specific qPCR with hydrolysis probes; the mutation results from cytological specimens and the primary tumors are highly concordant.

We carried out the mutation analysis for the following regions of these five genes: TP53 (exons 4 9), PIK3CA (exons 10 and 21), BRAF (exons 11 and 15), AKT1 (exon 3), and HRAS (exons 1 and 2).

We repeated the mutation analysis for TCGA exome-sequencing data.

Mutation analysis for each tumour sample was performed at least two times.

Therefore, the optimization of KRAS mutations analysis for prescription of cetuximab and panitumumab in mCRC needs rapid and robust molecular biology techniques.

Thus, hypermethylation profile of HOXA4 gene also could be considered as an epigenetic biomarker, in addition to the BCR-ABL gene mutations analysis, for prediction of response to IM treatment among CML patients.

Although direct sequencing of UBE2QL1 in 17 RCC cell lines and 116 sporadic RCC did not detect intragenic mutations, analysis for copy number abnormalities using a custom-designed MLPA assay detected heterozygous UBE2QL1 deletions in 8/49 (16.3%) sporadic RCC (Fig.  2B).

For mutation analysis of the EEF1A2 gene, primer pairs were designed for each exon (see supplementary data).

Whole procedure was performed as previously described for the BRAF mutation analysis except for the annealing condition (30 seconds at 60°C).