Sentence examples for mutation analyses of from inspiring English sources

Mutation analyses of the respective amino acids verified their importance for cofactor binding and enzyme activity.

Modeling and mutation analyses of RrQR indicated a novel mechanism underlying the stereospecific reaction led by a characteristic interaction, explaining how optically pure (R -3-quinuclidinol is synthesized fR -3-quinuclidinolne.

Modeling and mutation analyses of the catalytic site indicated that the hydrophobicity of two residues, I167 and F212, determines the substrate-binding orientation as well as the substrate-binding affinity.

Structural and mutation analyses of TR enzymes have indicated that the enzymes utilize electrostatic interactions between an amine group of the substrate and the carboxyl group of a Glu residue to determine the substrate-binding orientations (Nakajima et al. 1998; Nakajima et al. 1999).

Previous gene knockout results as well as mutation analyses of specific human cardiomyopathies have suggested that among the various AC constituents, the desmosomal plaque protein, plakophilin-2, plays a particularly important role in the formation, architectural organization and stability of these junctions interconnecting mature cardiomyocytes.

We also performed mutation analyses of two modulators of PIK3CA activity, PTEN and PIK3R1.

We use mutation analyses to explore which elements of secondary structure may be critical to p28 binding.

Although high-grade fetal adenocarcinoma was not present in every tumour sample, the diagnosis of pulmonary carcinosarcoma was finally made based on the mutation analyses, particularly of beta-catenin.

When patients received neoadjuvant radiotherapy, diagnostic tumor biopsies were used for mutation analyses instead of primary tumors.

A further obstacle for the interpretation of large-scale somatic mutation analyses is that fitness effects of the vast majority of mutations are unknown.

Wikis also provide an effective solution to the enduring problem of unpublishable or negative results (for example, of mutation analyses).